ea0029s18.2 | Molecular mechanisms in autoimmune thyroid disease | ICEECE2012
Bednarczuk T.
GravesÂ’ disease (GD) is a heterogeneous disorder affecting with varying degrees of severity the thyroid and eyes. This variety may suggest that complex interactions between genetic, environmental and endogenous factors influence the clinical course of GD. Although the genetic predisposition to GD is well established, the significance of genotype-phenotype correlations remains controversial. Moreover, the lack of complete phenotypic concordance in twin studies suggested th...